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Energy & Recovery · Longevity

NAD+

A cellular co-enzyme central to energy production, DNA repair, and the kind of steady mental clarity that age tends to soften — replenished where it's needed.

From $159 / month
Lab-verified 503A / 503B accredited Clinician-reviewed
A clean editorial product photograph for NAD+ in soft natural light
Form
Subcutaneous injection or nasal
Cadence
2× weekly (subQ) · daily (nasal)
Onset
First effects in 2–4 weeks
Pharmacy
503A / 503B accredited
What it is

Replenishing the molecule that runs the cell.

Nicotinamide adenine dinucleotide — NAD+ — is one of the most fundamental molecules in human biology. It's a co-enzyme present in every cell, central to energy production in the mitochondria, DNA repair, and the activity of sirtuin enzymes that influence cellular aging. Levels decline measurably with age, stress, alcohol use, and chronic illness.

Oral NAD+ precursors like NMN and NR raise levels modestly, but parenteral NAD+ — injection or intranasal — bypasses absorption losses and delivers the molecule itself. Members typically describe the experience not as stimulation but as restoration: steadier energy through the day, fewer afternoon flat-lines, sharper focus, and easier recovery.

Subcutaneous injection is dosed twice weekly and produces a stronger pulse with a longer interval. Intranasal is daily and gives a smoother curve — many members find it the easier rhythm to maintain. Your clinician will recommend the route that fits your goals.

Compounded NAD+ is dispensed only by accredited 503A U.S. pharmacies under your clinician's order, with each batch tested for potency, sterility, pH, and endotoxins.

Week by week

What to expect, in real time.

Every member's curve is a little different. The shape below is the typical clinician-guided arc.

1

Week 1 · Loading phase

You begin twice-weekly injections (or daily nasal). Many members notice steadier energy within seven to ten days.

2

Week 4 · Steady-state

Cellular pools approach saturation. Sleep quality, focus, and recovery typically feel more reliable.

3

Week 12 · Re-evaluation

Your clinician reviews response and may adjust cadence — some members step down, others hold the loading rhythm.

4

Week 24+ · Maintenance

A simpler weekly or daily rhythm keeps levels stable. Cycling on and off seasonally is also an option.

Who it's appropriate for

Honest eligibility — before you ever pay.

NAD+ isn't for everyone, and we don't pretend otherwise. Your clinician will confirm fit during your eligibility review.

A good fit for

  • Adults experiencing age-related changes in energy or mental clarity.
  • Members building a longevity protocol who want a foundational tool.
  • People with high oxidative load — frequent travel, training, or stress.
  • Anyone pairing NAD+ with glutathione, B-complex, or training recovery.

Not appropriate for

  • Active malignancy without specific clinical guidance.
  • Pregnancy or breastfeeding without specific clinical guidance.
  • Severe asthma flare-up (nasal route) without clinician clearance.
  • Anyone with a known allergy to NAD+ or its preservatives.
Common effects · what we do about them

What can happen — and how your clinician helps.

Common

Mild flushing

A brief warm or flushed feeling during or shortly after dosing is the most-reported sensation, especially with faster delivery. It resolves within minutes and tends to fade with adaptation.

Mild

Injection-site reaction

Mild redness or warmth at the IM/subQ site is uncommon and self-resolving. Rotate sites and warm the dose to room temperature.

Mild

Nasal irritation

Brief tingle or sniffle with the intranasal route is common in the first week. Saline rinse before dosing helps.

Rare

Headache or chest tightness

Usually tied to dosing speed. Slower injection or splitting the dose typically resolves it.

Pricing transparency

One flat price. No surprises.

Membership
$159/mo

Billed monthly. Pause or cancel from your dashboard in one click. Final price is set after clinician review and may vary based on dose and protocol.

Included
  • Clinician review & ongoing protocol
  • Medication and routine supplies
  • Temperature-controlled shipping
  • Async messaging with your clinician
  • Lab certificates of analysis on your dashboard
Not included
  • Insurance coverage (this is a cash-pay membership)
  • External lab fees if your clinician orders bloodwork
NAD+ FAQ

Treatment-specific questions.

How is this different from IV NAD+?
Same molecule. IV NAD+ delivers a large dose over several hours in a clinic setting. The MyPromise protocol uses subcutaneous or intranasal delivery for sustainable at-home use — slower, steadier elevations rather than a single acute peak. Most members get the benefits they want without the IV chair.
Should I do injection or nasal?
Both work. Injection is twice weekly and produces a stronger pulse; nasal is daily and gives a smoother curve. Members who travel or who don't want to manage syringes often prefer nasal. Your clinician will recommend based on your goals and lifestyle.
What about NMN or NR pills?
NMN and NR are NAD+ precursors and they do raise NAD+ levels — modestly. Parenteral NAD+ raises levels more directly and reliably. Some members combine an oral precursor with parenteral NAD+; others stick with one route. Your clinician will help you pick.
Will I feel a buzz?
Most members describe the effect as restorative rather than stimulating. Energy feels steadier, focus feels cleaner, sleep often deepens. If you feel jittery, the dose or delivery speed needs adjustment — message your clinician.
How long should I stay on it?
Most members run a loading phase of one to three months, then settle into a maintenance cadence. Some cycle on and off seasonally — your clinician can guide the rhythm.
Can I combine it with glutathione?
Yes — NAD+ and glutathione target related but distinct cellular pathways and are commonly paired in longevity protocols. Both are well-tolerated together.
Often paired with

Members who chose NAD+ often pair it with…

Ready when you are

A promise is just a plan with a witness.

Take the twelve-minute eligibility review. A licensed clinician will read your intake, recommend a protocol — or tell you honestly that we're not the right fit. Either way, you'll know within a day.